Oxidative Stress Assays Market Size, Share, and Trends 2024 to 2033

Oxidative Stress Assays Market Size and Growth

The global oxidative stress assays market size was USD 1.16 billion in 2023, calculated at USD 1.27 billion in 2024 and is expected to reach around USD 2.86 billion by 2033. The market is expanding at a solid CAGR of 9.46% over the forecast period 2024 to 2033. The oxidative stress assay benefits include high output analysis of many small molecule antioxidants and oxidation products from many sample sources like urine, saliva, blood, and blood cells, which will provide a truer and more comprehensive picture of the state of oxidative stress and antioxidant status of the whole body. These factors help to the growth of the market.

Oxidative Stress Assays Market Key Takeaways

• The North America oxidative stress assays market size reached USD 430 million in 2023 and is expected to attain around USD 1,070 million by 2033, poised to grow at a CAGR of 9.54% between 2024 and 2033.
• North America dominated the oxidative stress assays market with the largest revenue share of 37% in 2023.
• Asia Pacific is estimated to be the fastest-growing during the forecast period of 2024-2033.
• By product, the consumables segment has held a major revenue share of 45% in 2023.
• By test, the indirect assays segment has contributed more than 58% of revenue share in 2023.
• By test, the reactive oxygen species-based assays segment is the fastest-growing during the forecast period.
• By technology, the enzyme-linked immunosorbent assays (ELISA) segment has generated more than 37% of revenue share in 2023.
• By technology, the flow cytometry segment is estimated to grow significantly during the forecast period.
• By disease, the cardiovascular disease segment has recorded the biggest revenue share of 31% in 2023.
• By disease, the cancer segment is estimated to be the fastest-growing during the forecast period.
• By end-use, the pharmaceutical & biotechnology industries has captured more than 38% of revenue share in 2023.
• By end-use, the contract research organizations segment is estimated to be the fastest-growing during the forecast period.

U.S. Oxidative Stress Assays Market Size and Growth 2024 to 2033

The U.S. oxidative stress assays market size was exhibited at USD 300 million in 2023 and is projected to be worth around USD 760 million by 2033, poised to grow at a CAGR of 9.74% from 2024 to 2033.

North America dominated the oxidative stress assays market in 2023. The presence of many healthcare infrastructures, research institutes, and pharmaceutical & biotechnology industries helps the growth of the market in North America. The U.S. is the leading country for the growth of the market in the North American region.

Asia Pacific is estimated to be the fastest-growing during the forecast period of 2024-2033. Increased investment in research and development by research institutes, pharmaceutical industries, and government funding helps the growth of the oxidative stress assays market in the Asia Pacific region.

• In May 2023, a clinical flow cytometry system was launched by Sysmex Corporation in Japan. This technology is used for the diagnosis and analysis of hematological diseases like malignant lymphoma and leukemia.

Market Overview

The oxidative stress assays market deals with clinical laboratories, contract research organizations, academic research institutes, and pharmaceutical & biotechnology industries for various applications, including screening drug candidates, analyzing antioxidant qualities, and determining how they affect pathways linked to oxidative stress. Oxidative stress assays may measure levels of cellular antioxidants or levels of toxic reactive oxygen species.

Many types of tests are available on the market, including reactive oxygen species-based assays, enzyme-based assays, antioxidant capacity assays, indirect assays, etc. These factors help to the growth of the market. Oxidative stress is an imbalance of antioxidants and free radicles in the body that leads to cell damage and diseases like cancer, heart disease, and Alzheimer’s disease. There is a need for oxidative stress assays and products like consumables, services, and instruments that help the growth of the market.

Oxidative Stress Assays Market Growth Factors

• The applications of oxidative stress assays include screening drug candidates, determining how they affect the pathways linked to oxidative stress, and analyzing antioxidant qualities.
• Imbalance of antioxidants and free radicles in the body, which leads to cell damage and diseases like cancer, heart disease, and Alzheimer’s disease, which need oxidative stress assay.
• Oxidative stress assays are helpful in improving cancer and other disease treatments, which helps the growth of the market.
• Oxidative stress assay kit benefits include quantitative measurement and quantifying extracellular and intracellular oxidative stress levels. These factors help the growth of the oxidative stress assays market.

Oxidative Stress Assays Market Scope

Oxidative Stress Assays Market Dynamics

Driver

Increasing cases of chronic diseases

An increasing imbalance of antioxidants and free radicles in the body leads to cell damage and chronic diseases like cancer, heart disease, and Alzheimer’s disease, which need oxidative stress assays. Free radicles are increased due to both exogenous and endogenous sources. Ischemia, inflammation, cancer, infection, immune cell activation, aging, mental stress, and excessive exercise are all responsible for endogenous free radicle production. These factors help the growth of the oxidative stress assays market.

Restraint

High cost and lack of awareness

High cost and lack of awareness related to oxidative stress assay products like instruments, services, and consumables may restrict the growth of the market. Lack of skilled professionals and lack of awareness leads to higher turnover, overconfidence, poor judgment, and reduced team success. Disadvantages in protein-based assay include error-proneness with complex samples or protein mixtures, absorbance being affected by ionic strength and pH, and sensitivity to contamination from salts, buffers, and biological materials. These factors may restrict the growth of the oxidative stress assays market.

Opportunity

Research & development and advanced technologies

Increased research & development activities in pharmaceutical and biotechnology companies, academic research institutes, cosmetic companies, contract research organizations, and clinical laboratories help to the growth of the market. Use of advanced oxidative stress assay kits and reagents for the growth of the market. XF Palmitate advanced assay oxidation stress kit, dyes, and kits used for measurement of oxidative stress can help the growth of the market. These factors help the growth of the oxidative stress assays market.

Product Insights

The consumables segment dominated the market in 2023, and it is estimated to be the fastest-growing segment in the forecast period. Consumables for oxidative stress assays include kits and reagents. The benefits of an oxidative stress detection assay kit include early detection, which helps to early detection of oxidative stress occurrence, a quantitative measurement that evaluates intracellular and extracellular oxidative stress levels, and it also provides an intracellular and extracellular oxidative stress view in different cellular compartments. These factors help to the growth of the consumables segment and contribute to the growth of the oxidative stress assays market.

Test Insights

The indirect assays segment dominated the market in 2023. Indirect assays include nucleic acid-based assay, lipid-based assay, and protein-based assay for the detection of oxidative stress. Nucleic acid-based assays are used to detect coronavirus infections, infectious diseases, etc., and organism-specific RNA or DNA sequences extracted from the microorganism. Lipid-based assays are used for the measurement of plasma concentration of triglycerides, cholesterol, LDL- and HDL-cholesterol, determination of lipoprotein, and calculation of non-HDL cholesterol concentration, and they help clinicians to quantify lipid-associated health risks and monitor the effects of treatment.

The protein-based assay is highly used for diagnosing, monitoring, and treatment of cancer patients. These factors help the growth of the indirect assays segment and contribute to the growth of the oxidative stress assays market.

The reactive oxygen species-based assays segment is expected to be the fastest-growing during the forecast period. The ROS (reactive oxygen species) are natural byproducts of cellular oxidative metabolism and play a significant role in the transformation of cell death, cell survival, inflammation-related factor production, cell signaling, and differentiation. Reactive oxygen species contain oxygen radicals, which are highly reactive substances, and these are the key components in cancer therapies. These factors help the growth of the reactive oxygen species-based assays and contribute to the growth of the oxidative stress assays market.

Technology Insights

The enzyme-linked immunosorbent assays (ELISA) segment dominated the market in 2023, and it is estimated to be the fastest-growing segment during the forecast period. ELISA tests are simple equipment that uses basic mix-and-wash protocols, which makes them easy to perform in the lab. The basic reagent, the antibody, binds to its target with affordability and offers results with high specificity and high sensitivity. ELISA assays are used highly to detect antibodies, viruses, and autoantigens in whole blood or serum. These factors help the growth of the enzyme-linked immunosorbent assays (ELISA) segment and contribute to the growth of the oxidative stress assays market.

• In December 2023, a quantitative enzyme-linked immunosorbent assay (ELISA) was launched by Neogen Corporation for the detection of walnut allergens.

The flow cytometry segment is expected to grow significantly during the forecast period. Flow cytometry is a powerful tool for functional studies, disease research, immunophenotyping, and cell analysis. The benefits of flow cytometry include the ability to collect information from millions of cells in a few moments and to measure a high number of parameters on the same sample. The results of flow cytometry are used for monitoring the health of people who suffer from HIV, for cancer diagnosis and treatment, and for other purposes. It may also be helpful for doctors to figure out how serious a cancer can be and how it will respond well to a specific treatment. These factors help to grow the flow cytometry segment and contribute to the growth of the oxidative stress assays market.

• In June 2023, a new robotic system was launched by BD FACSDuet Premium System to automatic sample preparation for greater standardization in clinical flow cytometry diagnostics.

Disease Insights

The cardiovascular disease segment dominated the market in 2023. Oxidative stress assay is helpful for the treatment of cardiovascular disease. Cardiovascular disease may affect the heart and the blood vessels. Oxidative stress plays an important role in generating ROS (reactive oxygen species). An oxidative stress assay is needed to reduce oxidative stress in cardiovascular disease. These factors help the growth of the cardiovascular disease segment and contribute to the growth of the oxidative stress assays market.

The cancer segment is expected to be the fastest-growing during the forecast period. The oxidative stress assay can detect heterogeneous reactive oxygen species and antioxidant production in tumors and across lesions. These factors help to the growth of the cancer segment and contribute to the growth of the oxidative stress assays market.

• In November 2023, the PD-L1 test for the evaluation of PD-L1 protein expression on CTCs (Circulating Tumor Cells) to support cancer therapy studies was launched by a liquid biopsy company, Angle, with a CTC diagnostics solution for use in clinical oncology research, and drug development.

End-use Insights

The pharmaceutical & biotechnology industries segment dominated the oxidative stress assays market in 2023. In the pharmaceutical & biotechnology industries, new treatments and many therapeutic drug developments, rapid and precise development of vaccines and medicine can help the growth of the market.

The contract research organizations segment is estimated to be the fastest-growing during the forecast period. The benefits of contract research organizations include bringing new treatments, accelerating drug development, flexibility in services provided on a contract basis, increased efficiency because of specialized support, reduced cost as compared to conducting trials in-house and acquiring expert knowledge and resources in clinical research. These factors help to the growth of the contract research organizations and contribute to the growth of the oxidative stress assays market.

Recent Developments

• In April 2022, to enhance tilapia production with functional yeast to improve gut health and help disease prevention, an evidence-based program, Aquasaf Tilapia, was launched by an international biotechnology research company, Phileo by Lesaffre. The program addressed some serious problems faced by tilapia procedures, such as reduced growth linked with oxidative stress, economic losses because of poor gut health, and mass mortalities caused by pathogens.
• In November 2023, new active plant cells were launched by Meet Naolys’ which are based on the Goji plant, Lycium barbarum. This is for skin care because life exposes our skin to many endogenous and environmental factors. It is critical to address skin problems, oxidative stress/damage, pigmentation irregularities, and inflammation to ensure even-toned, healthier, and radiant skin.

Oxidative Stress Assays Market Companies

• OXFORD BIOMEDICAL RESEARCH
• Thermo Fischer Scientific Inc.
• QIAGEN
• Promega Corporation
• ImmunoChemistry Technologies
• Merck KGaA
• Enzo Life Sciences, Inc.
• Cell Biolabs, Inc.
• AMSBIO
• Abcam Limited
• Toxys B.V.
• Genox Corporation
• Hycult Biotech
• MEGA TIP San. Tic. Ltd. Sti.
• Kamiya Biomedical Company
• Callegari SRL
• Arbor Assays
• Eagle Biosciences, Inc.
• BioVision, Inc.

Segments Covered in the Report

By Product

• Instruments
• Consumables
  • Kits
  • Reagents
• Services

By Test 

• Indirect Assays
  • Protein-Based Assays
  • Lipid-Based Assays
  • Nucleic Acid-Based Assays
• Antioxidant Capacity Assays
  • Glutathione Assays
  • Ascorbic Acid Assays
  • Cell-Based Exogenous Antioxidant Assays
• Enzyme-Based Assays
• Reactive Oxygen Species-Based Assays

By Technology

• Enzyme-linked Immunosorbent Assay (ELISA)
• Flow Cytometry
• Chromatography
• Microscopy
• Others

By Disease

• Cardiovascular Disease
• Respiratory Disease
• Cancer
• Diabetes
• Others

By End-use

• Pharmaceutical & Biotechnology Industries
• Academic Research Institutes
• Contract Research Organizations
• Clinical Laboratories
• Others

By Geography

• North America
• Asia Pacific
• Europe
• Latin America
• Middle East & Africa